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2025 NFL AFC, NFC Title Odds: Bills, Colts Tied in AFC; Rams Favored in NFC

News RoomBy News RoomNovember 18, 2025No Comments4 Mins Read
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We’re past the midway point of the 2025-26 NFL season. The Super Bowl will be here before you know it. 

With that, let’s look at the odds at DraftKings Sportsbook as of Nov. 18 for which two teams will win their respective conferences and meet in the Big Game, as well as what to know about the AFC and NFC championship race. 

This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports.

AFC Conference winner

Bills: +400 (bet $10 to win $50 total)
Colts: +400 (bet $10 to win $50 total)
Chiefs: +550 (bet $10 to win $65 total)
Broncos: +550 (bet $10 to win $65 total)
Ravens: +600 (bet $10 to win $70 total)
Patriots: +600 (bet $10 to win $70 total)
Chargers: +2200 (bet $10 to win $230 total)
Jaguars: +2500 (bet $10 to win $260 total)
Texans: +3500 (bet $10 to win $360 total)
Steelers: +4500 (bet $10 to win $460 total)

What to know: There’s a tie at the top of the board and the Chiefs are not involved in it. Kansas City has at least made it to the AFC title game in seven straight seasons, and has made it to the Super Bowl five out of the last seven years. In addition, over the last seven years, the AFC title game has taken place in Kansas City six times. However, it finally appears that the Chiefs are … human? They have lost two in a row, at Buffalo and at Denver, and now are 5-5 on the year. Speaking of Buffalo, after a win over Kansas City in Week 9, and a weird loss at Miami in Week 10, the Bills earned a 44-32 victory over Tampa Bay in Week 11. Four of their next five are on the road, including a huge one at New England in Week 15. Tied with Buffalo are the Colts, who suffered just their second loss of the season in Week 9 at Pittsburgh, but bounced back with a Week 10 win over Atlanta. They had a bye in Week 11. Meanwhile, the Broncos, who just beat Kansas City, are tied with K.C. at third on the board, while the Ravens, who have won four in a row, are tied with the 9-2 Pats in fifth.

NFC Conference winner

Rams: +275 (bet $10 to win $37.50 total)
Eagles: +280 (bet $10 to win $38 total)
Seahawks: +500 (bet $10 to win $60 total)
Lions: +600 (bet $10 to win $70 total)
Packers: +800 (bet $10 to win $90 total)
Buccaneers: +1400 (bet $10 to win $150 total)
49ers: +1400 (bet $10 to win $150 total)
Bears: +3500 (bet $10 to win $360 total)
Cowboys: +9000 (bet $10 to win $910 total)

What to know: The Rams aren’t slowing down. They have won five in a row, including a 21-19 win over division rival Seattle in Week 11. That was a big one, for the NFC West standings and the NFC standings. In four of its last five games, Los Angeles has allowed 39 total points, and in that other game, it allowed 26 to San Francisco in a wire-to-wire win. Just behind L.A. is one of the two teams it has lost to this season, the defending champion Eagles. They are on a four-game winning streak after losing two in a row in Weeks 5 and 6. Philly’s last two wins were at Green Bay and then at home against Detroit. In those two wins, despite scoring just 26 points, the Eagles allowed only 16 points. Allowing 16 total points to the fourth and fifth teams on this oddsboard is … impressive. 

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