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2026 AL Wild Card Odds: White Sox Win Game 1; Now Favored Over Astros

News RoomBy News RoomSeptember 30, 2026No Comments2 Mins Read
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A recent (polarizing) World Series winner takes on the team no one thought had a chance to be here.

Let’s check out the odds for Astros-White Sox at DraftKings Sportsbook as of Sept. 29, as well as what to know.

This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports.

AL Wild Card: Astros vs. White Sox

Houston Astros Chicago White Sox Series Winner

White Sox: -245 (bet $10 to win $14.08 total)
Astros: +195 (bet $10 to win $29.50 total)

Houston Astros Chicago White Sox Game 1 — CHW 6, HOU 3

Spread: Astros -1.5 (CHW covers)
Moneyline: Astros -123, White Sox +102 (CHW wins)
O/U: 8 (Over hits)

Houston Astros Chicago White Sox Game 2 (Sept. 30)

Spread: Astros -1.5
Moneyline: Astros -149, White Sox +123
O/U: 7.5

Here’s what to know about the Astros-White Sox odds:

Season Series: Houston won five of the seven regular-season matchups against Chicago, including three of the last four. 

Game 1: Would you believe that, prior to this season, Chicago had at least 100 losses in each of the last three seasons? It had 102 last year, a modern-era record 121 in 2024, and 101 in 2023. It’s for that reason that absolutely no one came into this season thinking they had a chance to make the playoffs. But here they are, and they have a 1-0 lead on Houston in the wild-card round, after winning Game 1, 6-3. Chicago took a 3-0 lead in the first two innings behind a sacrifice fly from Munetaka Murakami and a 2-run single from Sam Antonacci. It essentially cruised from there, bolstered by a solo home run from Colson Montgomery in the top of the fourth. Game 2 is Wednesday in Houston.

The White Sox last made the playoffs in 2021, and last won a playoff series in 2005, the same year they last won the World Series. As for the Astros, they finished 81-81 in the regular season, but it was still good enough to win the AL West. The Astros are the only team in the postseason that had a negative run differential in the regular season, having been outscored by 32 runs.

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